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malar

Rheumatology/DermatologyIntegumentaryMusculoskeletalCardiovascularImmune

Summary

Malar refers to the cheek or cheekbone region, specifically the zygomatic area of the face. It is most notably used in describing the 'malar rash' seen in systemic lupus erythematosus (SLE).

Detail

The term 'malar' pertains to the zygomatic (cheek) bone and the overlying soft tissue of the cheek region. Clinically, it is most commonly referenced in the context of the 'malar rash' or 'butterfly rash' seen in systemic lupus erythematosus, which is an erythematous, raised rash over the malar eminences and bridge of the nose, characteristically sparing the nasolabial folds. This sparing helps distinguish it from other facial rashes like seborrheic dermatitis or rosacea. The malar rash is often photosensitive, worsening with sun exposure, and is one of the 11 classification criteria (SLICC/ACR) for SLE. Pathophysiology involves immune complex deposition and interface dermatitis at the dermal-epidermal junction, with UV light exposure triggering keratinocyte apoptosis and subsequent autoantigen exposure. 'Malar flush' is another related finding—a bluish-purple discoloration of the cheeks classically associated with mitral stenosis, caused by chronic low cardiac output and peripheral vasoconstriction leading to cutaneous vasodilation of capillaries with deoxygenated blood. The malar region is also relevant in facial fracture classification (e.g., malar/zygomatic complex fractures from trauma, causing flattening of the cheek and possible infraorbital nerve involvement).

Sources

  • First Aid for the USMLE Step 1
  • Robbins Basic Pathology
  • UpToDate: Overview of cutaneous lupus erythematosus
  • Harrison's Principles of Internal Medicine

Reviewed by Medusa editorial — medical student review. Information here is for study reference only and is not medical advice. Spotted an error? Let us know.

malar — Medical Glossary