heritability
Summary
Heritability is the share of variation in a trait, within a given population and environment, that is due to genetic differences (all genetic variance in broad-sense, additive only in narrow-sense). It is not how genetic a trait is in one person.
Detail
Meaning: Heritability is the proportion of variation in a trait, within a particular population and environment, that is due to genetic differences among individuals. It describes variation, not how much genes contribute to a trait in one person. Broad-sense heritability counts all genetic variance; narrow-sense counts additive effects alone. Less environmental variation raises heritability, though the genes are unchanged.
Equation: H² = VG / VP, where VG is genetic variance, VP is total phenotypic variance, and VP = VG + VE (VE is environmental variance). Variances carry the trait's unit squared, so H² is unitless, between 0 and 1. Narrow-sense: h² = VA / VP, where VA is additive genetic variance.
On the MCAT: Passages use twin and adoption studies. Higher concordance in monozygotic than dizygotic twins, or adoptees resembling biological more than adoptive parents, points to higher heritability. Predict that a more uniform environment raises heritability and a more varied one lowers it.
Common confusion: High heritability does not mean a trait is fixed, and it does not explain differences between groups. Height is highly heritable within a population, yet average height can rise across generations with better nutrition.
Sources
- Campbell Biology
- Introduction to Genetic Analysis
Written for the MCAT and checked before it was published. For study reference only. Spotted an error? Let us know.